ManAudit doesn't introduce new clinical thresholds — it operationalizes established reporting and quality-appraisal standards and applies them as a consistency and coherence check. The audit logic draws on the following.
Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71.
Flow-diagram arithmetic and reporting completeness for systematic reviews.
Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology (MOOSE): a proposal for reporting. JAMA. 2000;283(15):2008-2012.
Reporting standard for meta-analyses of observational data.
von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP; STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement. Lancet. 2007;370(9596):1453-1457.
Reporting standard for observational and registry analyses.
Reitsma JB, Glas AS, Rutjes AWS, Scholten RJPM, Bossuyt PM, Zwinderman AH. Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. J Clin Epidemiol. 2005;58(10):982-990.
Basis for flagging separately-pooled, internally incoherent diagnostic summary points; bivariate model as the standard.
Rutter CM, Gatsonis CA. A hierarchical regression approach to meta-analysis of diagnostic test accuracy evaluations. Stat Med. 2001;20(19):2865-2884.
HSROC modeling for diagnostic-accuracy synthesis.
Whiting PF, Rutjes AWS, Westwood ME, et al. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011;155(8):529-536.
Risk-of-bias appraisal for diagnostic studies.
Wells GA, Shea B, O'Connell D, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Ottawa Hospital Research Institute.
Quality appraisal of cohort and case-control studies; basis for scrutinizing non-discriminating uniform scores.
Youden WJ. Index for rating diagnostic tests. Cancer. 1950;3(1):32-35.
Youden index consistency check (sensitivity + specificity − 1).